Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

An ethnopharmacological review of Hyptis suaveolens (L.) Poit

Rong Li, Gengqiu Tang, Xile Liu, Junni Li, Dong Wang, Shengguo Ji

School of Chinese Traditional Medicine, Guangdong Pharmaceutical University, Guangdong 510006, PR China;

For correspondence:- Shengguo Ji Email: shengguo_ji@163.com Tel:+8618027342788

Accepted: 22 June 2020 Published: 31 July 2020

Citation: Li R, Tang G, Liu X, Li J, Wang D, Ji S. An ethnopharmacological review of Hyptis suaveolens (L.) Poit. Trop J Pharm Res 2020; 19(7):1541-1550 doi: 10.4314/tjpr.v19i7.29

© 2020 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

This review aimed to provide a comprehensive overview of ethnobotanical uses, chemical constituents, posology, and toxicology of Hyptis suaveolens, and to address the significant medicinal benefits in order to promote its application. An extensive and systematic review of the literature was undertaken and all relevant abstracts and full-text articles analyzed and included in the review. A wide range of traditional uses are cited in the literature, ranging from uses for malaria, constipation, stomach problems, renal inflammation to external uses in repelling insects and treating injuries such as lacerations and burn-related damage to skin and tissues. To date, pharmacological studies have demonstrated the significant activities of this plant that support uses such as antimicrobial, antidiabetic, antiulcer, and anti-inflammatory. Numerous important phytochemicals, including 6 triterpenes, 8 diterpenes and 1 flavonoid have been isolated, identified and reported. The extracts and phytochemicals isolated from the plants show considerable potential for medicinal exploitation and utilization, including antimitotic, anti-proliferative, cytotoxic, antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, anti-secretory, hepatoprotective, insecticidal, and acaricidal activities. As a medicinal plant, H. suaveolens is endowed with immense exploitation and utilization value and is widely used worldwide Therefore, further studies to fully elucidate its medicinal potential are warranted.

Keywords: Hyptis suaveolens (L.) Poit, Ulcer Antimicrobial Inflammation, Diterpenes, Traditional medicine, Ethnopharmacology, Lamiaceae