Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

Current Knowledge on Microarray Technology - An Overview

Chitrala Kumaraswamy Naidu, Yeguvapalli Suneetha

Department of Zoology, Sri Venkateswara University, Tirupati -517502, India;

For correspondence:- Yeguvapalli Suneetha Email: ysuneethareddy4@gmail.com Tel:+919985563644

Received: 19 April 2011 Accepted: 19 December 2011 Published: 21 February 2012

Citation: Naidu CK, Suneetha Y. Current Knowledge on Microarray Technology - An Overview. Trop J Pharm Res 2012; 11(1):153-164 doi: 10.4314/tjpr.v11i1.20

© 2012 The authors.
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Abstract

The completion of whole genome sequencing projects has led to a rapid increase in the availability of genetic information. In the field of transcriptomics, the emergence of microarray-based technologies and the design of DNA biochips allow high-throughput studies of RNA expression in cell and tissue at a given moment. It has emerged as one of the most important technology in the field of molecular biology and transcriptomics. Arrays of oligonucleotide or DNA sequences are being used for genome-wide genotyping and expression profiling, and several potential clinical applications have begun to emerge as our understanding of these techniques and the data they generate improves. From its emergence to date, several database, software and technology updates have been developed in the field of microarray technology. This paper reviews basics and updates of each microarray technology and serves to introduce newly compiled resources that will provide specialist information in this area.

Keywords: Microarray, Databases, cDNA array, Oligonucleotide array