Florence E Eichie , Roland S Okor
Department of Pharmaceutics and Pharmaceutical Technology, University of Benin, P.M.B. 1154, Benin City, Nigeria.;For correspondence:- Florence Eichie Email: eichie@uniben.edu
Published: 24 June 2002
Citation: Eichie FE, Okor RS. Effect of acid treatment on the consolidation and plasto-elasticity of tapioca powder. Trop J Pharm Res 2002; 1(1):45-49 doi: 10.4314/tjpr.v1i1.7
© 2002 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
Method: The parameters measured were the degree of consolidation of the powder after compression (i.e. the packing fraction of resulting tablets), the plasto-elasticity of the powders as reflected by the brittle fracture index (BFI) of the tablets made from the powders and the viscosities of mucilages derived from the powders. The influence of time of exposure and the concentration of acid used in the treatment were studied.
Results: The degree of consolidation of the powder increased slightly with increase in duration of exposure to acid (24 – 72 h) but drastically with increase in the acid concentration from 0.1 to 0.4 mol. L –1 . On the other hand, the plasto-elasticity of the powders as measured by the BFI values and the viscosities of mucilages derived from the powders decreased slightly with duration of exposure but drastically with increase in acid concentration. A change in acid concentration was therefore the more determinant factor with regards to the consolidation and plasto-elasticity properties of the powders. The decrease in the viscosities of the mucilages following acid
treatment of the powders was indicative of a breakdown of polymeric structure in the powder
Conclusion: Acid treatment of tapioca powder imparted plasticity in tapioca powder which became compressible.
Archives
News Updates