Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats

Sarawoot Palipoch¹ , Phanit Koomhin¹, Chuchard Punsawad¹, Prasit Suwannalert²

¹School of Medicine, Walailak University, 222 Thaiburi, Thasala District, Nakhon Si Thammarat, 80161; ²Department of Pathobiology, Faculty of Science, Mahidol University, 272 Rama VI Road, Ratchathewi District, Bangkok 10400, Thailand.

For correspondence:- Sarawoot Palipoch Email: sarawoot.pa@wu.ac.th Tel:+6675672873

Accepted: 14 March 2019 Published: 30 April 2019

Citation: Palipoch S, Koomhin P, Punsawad C, Suwannalert P. Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats. Trop J Pharm Res 2019; 18(4):823-828 doi: 10.4314/tjpr.v18i4.20

© 2019 The authors.
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Abstract

Purpose: The rate of gastrointestinal adenomatous polyps, often regarded as precancerous lesions, developing into cancer is 40 – 70 %. Endoscopic resection has been the preferred method for treating gastric polyps since the late 1960s. Surgical removal of polyps continues to play an important role in the treatment of polyps; however, the efficacy of such treatment cannot be guaranteed, and polyps may recur.

Case presentation: Here, we report a 44-year-old man suffering from gastrointestinal polyps who refused surgical treatment and instead was treated with traditional Chinese herbal medicine (TCHM) for approximately 1 year. The patient was diagnosed with “qi deficiency and dampness syndrome” based on traditional Chinese medicine theory and was treated with the TCHM “strengthen qi and remove dampness formula”, referred to as the shen-ling-bai-zhu powder/decoction.

Conclusion: This case suggests that TCHM may play an important role in the treatment of gastrointestinal polyps. Relevant data are, however, limited and a randomized controlled trial is needed to confirm TCHM efficacy in a larger population.

Keywords: Case study, Gastrointestinal polyps, Traditional Chinese herbal medicine, Shen-ling-bai-zhu powder