Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Effect of different conization ranges on pregnancy outcomes

Yue Wang, Shasha Liu, Jixiao Liu, Yuling Guo, Pengpeng Qu

Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, 300100, China;

For correspondence:- Pengpeng Qu Email: qu.pengpeng@hotmail.com

Accepted: 08 March 2022 Published: 31 March 2023

Citation: Wang Y, Liu S, Liu J, Guo Y, Qu P. Effect of different conization ranges on pregnancy outcomes. Trop J Pharm Res 2023; 22(3):693-698 doi: 10.4314/tjpr.v22i3.29

© 2023 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To analyze the influence of different conization on pregnancy outcomes.

Methods: The data of 78 women at childbearing age having cervical conization in our hospital from January 2013 till December 2015, was collected and analyzed. The control group comprised of 80 women of childbearing age with matched clinical data, who did not undergo cervical conization. Data on the conization procedure were analyzed and pregnancy and obstetric outcomes were assessed. using the. Comparisons were made using the ï£2test or the Fisher exact test and Student T-test as appropriate.

Results: Cold knife cervical conization prolonged the time to conception in patients. Following the procedure, the incidence of premature delivery and premature rupture of membranes were significantly increased as also the rate of early abortions. The depth and circumference of conization was found to be directly correlated with the rate of premature delivery and premature membrane rupture, but not with fetal growth restriction and macrosomia.

Conclusion: The depth and circumference of resection should be based on the type of cervical lesions as well as the prognosis and the future pregnancy plans of the patients.

Keywords: Cervical conization; cold knife conization; cervical intraepithelial neoplasia; conization depth; conization circumference