Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Evaluation of the Antibacterial Activity of 14 Medicinal Plants in Côte d´Ivoiré

GEK Bolou¹, I Bagré¹ , K Ouattara¹, A J Djaman^1,2

¹Biochemical Pharmacodynamy Laboratory, Biosciences Department, Cocody University, Abidgan; ²Biochemical Laboratory of Pasteur Institute of Côte d'Ivoire, Abidgan.

For correspondence:- I Bagré Email: bagrefreefr@yahoo.fr Tel:+22508008901

Received: 10 July 2010 Accepted: 24 April 2011 Published: 24 June 2011

Citation: Bolou G, Bagré I, Ouattara K, Djaman AJ. Evaluation of the Antibacterial Activity of 14 Medicinal Plants in Côte d´Ivoiré. Trop J Pharm Res 2011; 10(3):335-340 doi: 10.4314/tjpr.v10i3.3

© 2011 The authors.
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Abstract

Purpose: To evaluate the antibacterial potentials of fourteen ethnobotanically selected plants traditionally used in different parts of Côte d’Ivoire for the treatment of typhoid fever and gastrointestinal disorders.

Method: The antimicrobial activity of the extracts of the plant was tested against a collection strain of Salmonella typhimurium, a clinical strain of Salmonella typhi and Pseudomonas aeruginosa by macrobroth dilution method. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined.

Results: All the plants had bactericidal activity against at least one of the test microorganisms with both MIC and MBC ranging from 2.5 to > 80 mg/ml. Among the plant extracts, Terminalia glaucescens. (Combretaceae) Bersama abyssinica subsp. paullinioides (Melianthaceae ) and Abrus precatorius (Fabaceae) showed the most promising broad spectrum antibacterial properties, inhibiting all of the strains tested, especially S. Typhi and P. aeruginosa, with MBC ranging from 2.5 to 5 mg/ml.

Conclusion: The findings provide support for the use of these plants in traditional medicine for treatment of typhoid fever and gastrointestinal disorders, and are thus, potential sources of drugs that would need to be subjected to further studies.

Keywords: Antimicrobial activity, Ivorian medicinal plants, MIC, MBC