Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Evaluation of the clinical effect of kangaroo-style intervention mode on neonatal cerebral palsy treated with mouse nerve growth factor

Hui Yang, Dan Sun, Chunling Gao

Wuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Institute of Maternal and Child Health, Wuhan 430016, Hubei, China;

For correspondence:- Chunling Gao Email: 13545163164@163.com

Accepted: 7 July 2024 Published: 31 July 2024

Citation: Yang H, Sun D, Gao C. Evaluation of the clinical effect of kangaroo-style intervention mode on neonatal cerebral palsy treated with mouse nerve growth factor. Trop J Pharm Res 2024; 23(7):1157-1163 doi: 10.4314/tjpr.v23i7.15

© 2024 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To investigate the effect of application of kangaroo-style intervention mode on neonatal cerebral palsy treated with mouse nerve growth factor.

Methods: In this retrospective study, 153 newborns with cerebral palsy on admission to Wuhan Maternal and Child Healthcare Hospital, China between January 2016 and January 2020 were assigned to control group (n = 81) and study group (n = 72), based on differences in intervention schemes used. The control and study groups received mouse nerve growth factor and routine intervention, while study group received additional treatment with kangaroo-style intervention mode. After treatment, neonatal neurological function, intellectual development, intelligence development quotient, and growth and development indices were compared between the two groups.

Results: Scores on neurological function, mental development index and psychomotor development index, as well as intelligence development quotient were significantly higher in the study group than in the control group (p < 0.05). There were no significant differences in growth and development indices between the two groups (p > 0.05).

Conclusion: Kangaroo-style intervention mode effectively improves neurological function, and promotes intellectual development in cerebral palsy newborns treated with mouse nerve growth factor. However, it had no significant effect on neonatal physical development.

Keywords: Kangaroo-style intervention, Cerebral palsy, Mouse nerve growth factor, Newborns