Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Galangoflavonoid Isolated from Rhizome of Alpinia galanga (L) Sw (Zingiberaceae)

S B Jaju¹ , N H Indurwade¹, D M Sakarkar¹, N K Fuloria², M D Ali³, S Das⁴, S P Basu⁴

¹S.N. Institute of Pharmacy, Pusad, Amravati University, M.S -445 204; ²Ram-eesh Institute of Vocational and Technical Education, Knowledge Park-II, Greater Noida, UP 201 306; ³Department of Pharmacognosy, Jamia Hamdard, New Delhi, 110 062; ⁴Department of Pharmaceutical Technology, NIET, Knowledge park - II, Greater Noida, UP, 201 306, India.

For correspondence:- S Jaju Email: shivanijaju@rediffmail.com Tel:09911225981

Received: 7 March 2009 Accepted: 02 October 2009 Published: 21 December 2009

Citation: Jaju SB, Indurwade NH, Sakarkar DM, Fuloria NK, Ali MD, Das S, et al. Galangoflavonoid Isolated from Rhizome of Alpinia galanga (L) Sw (Zingiberaceae). Trop J Pharm Res 2009; 8(6):545-550 doi: 10.4314/tjpr.v8i6.10

© 2009 The authors.
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Abstract

Purpose: The purpose of this investigation was to isolate novel flavonoids from Alpinia galanga rhizomes.

Methods: The methanol extract of Alpinia galanga was subjected to column chromatography and eluted with ethyl acetate-methanol (9:1) to yield a compound, galangoflavonoside (AG 11). The structure of the compound was elucidated by various spectral techniques (UV, IR, ¹H NMR, ¹³C NMR, and MS).

Results: Chemical investigation of the extract furnished a new flavonoid galangoflavonoside (AG 11). Conclusion: The isolated compound, galangoflavonoside (AG 11,) could be a potential therapeutic compound as well as serve as a lead compound in the synthesis of other useful flavonoids. Isolation of the galangoflavonoside from Alpinia galanga rhizomes is being reported, to the best of our knowledge, for the first time.

Keywords: Alpinia galangal; Methanol extract; Galangoflavonoside; Spectral techniques