Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

Hypochlorous Acid - Analytical Methods and Antimicrobial Activity

Müjde Eryılmaz¹ , İsmail Murat Palabıyık²

¹Department of Pharmaceutical Microbiology; ²Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey.

For correspondence:- Müjde Eryılmaz Email: meryilmaz@ankara.edu.tr Tel:+903122033185

Received: 27 September 2012 Accepted: 5 January 2013 Published: 21 February 2013

Citation: Eryılmaz M, Palabıyık &M. Hypochlorous Acid - Analytical Methods and Antimicrobial Activity. Trop J Pharm Res 2013; 12(1):123-126 doi: 10.4314/tjpr.v12i1.20

© 2013 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Hypochlorous acid (HOCl) is produced by the human body’s immune cells to fight infections. It is effective against a broad range of microorganisms. It is non-toxic, non-irritant and non-corrosive at proper usage concentrations. There are some available commercial products that contain HOCl. However, its low storage stability constitutes a major challenge. This review considers the antimicrobial activity of HOCl and its methods of analysis.

Keywords: Antimicrobial activity, Hypochlorous acid, Analytical methods