Xiaoxv Dong1,
Jing Fu1,
Xingbin Yin1,
Xuechun Li1,
Bo Wang2,
Sali Cao1,
Jin Zhang1,
Hui Zhang1,
Yang Zhao1,
Jian Ni1 
For correspondence:- Jian Ni Email: njtcm@263.net Tel:+01084738607
Received: 6 June 2014 Accepted: 14 September 2014 Published: 19 October 2014
Citation: Dong X, Fu J, Yin X, Li X, Wang B, Cao S, et al. Pharmacological and other Bioactivities of the Genus Polygonum - A Review. Trop J Pharm Res 2014; 13(10):1749-1759 doi: 10.4314/tjpr.v13i10.27
© 2014 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
The genus Polygonum encompasses approximately 300 species widely distributed around the world, among which 120 Polygonum species grow in China. Among the rich species, 81 of them are widely used in traditional Chinese and folk medicines. In recent years, several studies have found that the genus Polygonum posseses a variety of biological activities including antioxidation, antimicrobial, anti-tumor, anti-obesity, etc. However, there are still not enough systemic data on the chemical constituents and their pharmacological effects; hence, it would be useful to review current literature for available pharmacological activites of the genus and as well as its active ingredients. Both in-vitro and in-vivo studies have provided strong evidence for the therapeutic potential of the genus Polygonum. This review collates and examines information on the pharmacological effects of the genus Polygonum as well as its chemical constituents.
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