Mohib Ullah Kakar1,2,
Muhammad Saeed3,
Ke Luo1,
Imran Suheryani1,
Wu Shuang1,
Yulin Deng1,
Rongji Dai1
For correspondence:- Rongji Dai
Email: dairongji@bit.edu.cn Tel:+861068949331
Accepted: 25 September 2019
Published: 31 October 2019
Citation:
Kakar MU, Saeed M, Luo K, Suheryani I, Shuang W, Deng Y, et al.
Phytochemistry and medicinal values of Mahonia bealei: A review. Trop J Pharm Res 2019; 18(10):2219-2227
doi:
10.4314/tjpr.v18i10.31
© 2019 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
Abstract
Purpose: To review the medicinal uses of Mahonia bealei, an important member of the genus Mahonia, with a focus on its various applications in Traditional Chinese Medicine, as well as published scientific evidence on its effectiveness.
Methods: Information in all available literature was retrieved using different search engines including NCBI, ISI Web of Knowledge and Google.
Results: Several compounds have been extracted from M. bealei. These include alkaloids, triterpenes, flavonoids, phytosterols and lignans. Traditionally, the plant is used to treat dysentery, diarrhea and inflammation. Globally, scientists have used in vitro and in vivo techniques to evaluate the usefulness of compounds extracted from M. bealei with respect to their antibacterial, anti-inflammatory, antitumor, antioxidant as well as anti-gastrin properties.
Conclusion: Different parts of this plant still remain underexplored. Moreover, comparison of the properties of the isolated compounds has not been carried out, nor are there reports on the synergistic effects of extracts of the plant. Therefore, future research to address these areas may be useful in the discovery of new therapeutic agents.
Keywords: Berberidaceae, Mahonia bealei, Traditional Chinese Medicine, Alkaloids, Flavonoids, Anti-inflammatory activity, Anti-tumor activity