Tropical Journal of Pharmaceutical Research

Short Communication | OPEN ACCESS

Studies of antimicrobial activity and chemical constituents of Ximenia americana

David S. Ogunleye , S. F. Ibitoye

Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu, Nigeria;

For correspondence:- David Ogunleye Email: pharmdavid2004@yahoo.com

Published: 17 December 2003

Citation: Ogunleye DS, Ibitoye SF. Studies of antimicrobial activity and chemical constituents of Ximenia americana. Trop J Pharm Res 2003; 2(2):239-241 doi: 10.4314/tjpr.v2i2.8

© 2003 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Ximenia americana is a plant that is used in traditional medicine for the treatment of malaria, leproutic ulcers and skin infections of mixed origin in Northern parts of Nigeria. To evaluate the scientific basis for the use of the plant, the antimicrobial activities of extract of the leaves were evaluated against six common bacterial isolates. Chemical constituents of the extract were also determined. The extract of was active against the test organisms including Escherischia coli, Pseudomonas aeruginosa and Candida albicans. Tannins, flavonoids, alkaloids, saponins, anthrax-quinones, starch, general glycosides and bitter principles were found to be present in the extract.

Keywords: Antimicrobial activity, chemical constituents leaves extract, Ximenia americana