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Original Research Article | OPEN ACCESS

Studies on Wound healing properties of Quercus Infectoria

S P Umachigi1 , K N Jayaveera2, CK Ashok Kumar3, G S Kumard4, Vrushabendra BM swamy5, DV Kishore Kumar6

1Department of Pharmaceutics,; 2Department of Chemistry, Jawaharlal Nehru Technological University College of Engineering, Ananthpur- 01, Andhra Pradesh, India,; 3Department of Pharmacognosy, Sree Vidyanikethan, College of Pharmacy, A.Rangamepeta, Chittoor Dist, Andhra Pradesh, India.; 4Department of Pharmacognosy,; 5Department of Pharmacology,; 6Department of Chemistry, Rural College of Pharmacy, D.S.Road, Devanahalli-562110 Karnataka, India..

For correspondence:-  S Umachigi   Email: umachigisanjay@yahoo.co.in

Published: 12 March 2008

Citation: Umachigi SP, Jayaveera KN, Kumar CA, Kumard GS, swamy VB, Kumar DK. Studies on Wound healing properties of Quercus Infectoria. Trop J Pharm Res 2008; 7(1):913-917 doi: 10.4314/tjpr.v7i1.7

© 2008 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose:   The aim of the present study was to investigate the wound healing activity of the selected Indian medicinal plant Quercus infectoria.
Method: Ethanol extract of the shade-dried leaves of Quercus infectoria was studied for its effect on wound healing in rats, using incision, excision and dead-space wound models, at two different dose levels of 400 and 800 mg/kg.
Result: The plant showed a definite, positive effect on wound healing, with a significant increase in the levels of the antioxidant enzymes, superoxide dismutase and catalase, in the granuloma tissue.
Conclusion: The efficacy of this plant in wound healing may be due to its action on antioxidant enzymes, thereby justifying the traditional claim.
 

Keywords: Quercus infectoria, wound healing, superoxide, catalase

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