Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Two Novel Non-Conventional Seed Oil Extracts with Antioxidant and Antimicrobial Activities

Lessoy T Zoué¹, Micaël E Bédikou¹, Jean T Gonnety², Betty M Faulet², Sébastien L Niamké¹

¹Laboratoire de Biotechnologies, FiliÃ¨re Biochimie-Microbiologie de lâ€™UnitÃ© de Formation et de Recherche en Biosciences de lâ€™UniversitÃ© de Cocody-Abidjan, 22 BP 582 Abidjan; ²Laboratoire de Biochimie et Technologie des Aliments de lâ€™UnitÃ© de Formation et de Recherche en Sciences et Technologie des Aliments de lâ€™UniversitÃ© dâ€™Abobo-AdjamÃ©, 02 BP 801 Abidjan 02, CÃ´te dâ€™Ivoire.

For correspondence:- Sébastien Niamké Email: niamkes@yahoo.fr Tel:+22507846409

Received: 13 September 2011 Accepted: 29 April 2012 Published: 15 June 2012

Citation: Zoué LT, Bédikou ME, Gonnety JT, Faulet BM, Niamké SL. Two Novel Non-Conventional Seed Oil Extracts with Antioxidant and Antimicrobial Activities. Trop J Pharm Res 2012; 11(3):469-475 doi: 10.4314/tjpr.v11i3.17

© 2012 The authors.
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Abstract

Purpose: To investigate the seed oils of Corchorus olitorius and Hibiscus sabdariffa for their antioxidant and antimicrobial potential.

Methods: The physicochemical characteristics of oil of the plant seeds were determined using standard methods while their volatile compounds were analyzed by gas chromatography coupled with mass spectrometery (GC-MS). The antioxidant activity of these oils was determined using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method, and their antimicrobial effect was determined by agar dilution method.

Results: Phospholipids, carotenoids and phenols contents of the studied seed oils were approximately 2.0 %, 100 mg/100g and 6.7 mg/100g, respectively. GC-MS analysis of the volatile compounds showed the presence of various aromatic and aliphatic organic compounds while the antioxidant activity of the oils was in the range of 0 to 5 g/l, which was higher than that of ascorbic acid. The seed oils also showed antimicrobial activity against Staphylococcus aureus, Aspergillus fumigatus and Trichophyton mentagrophytes with minimal inhibitory concentrations (MIC) of 250.0 and 62.5 mg/ml for C. olitorius and H. sabdariffa seed oils, respectively.

Conclusion: C. olitorius and H. sabdariffa seed oils showed pronounced antioxidant and antimicrobial activities. These characteristics should be exploited for possible applications in the food supplement, pharmaceutical and cosmetic industries.

Keywords: Corchorus olitorius, Hibiscus sabdariffa, Seed oil, Antioxidant activity, Antimicrobial activity