Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Frequencies of HBV, HCV, HIV, and Syphilis Markers Among Blood Donors: A Hospital-Based Study in Hodeidah, Yemen

Sultan Ayesh Mohammed Saghir¹ , Faisal Muti Al-Hassan¹, Omar Saeed Ali Alsalahi¹, Abdullah Ebrahim Abdul-Alaziz Alhariry², Huda Salman Baqir¹

¹Advanced Medical and Dental Institute, Universiti Sains Malaysia, Penang, Malaysia; ²Blood Bank Unit, Military Hospital, Hodeidah, Yemen.

For correspondence:- Sultan Mohammed Saghir Email: sultana1976@yahoo.com Tel:+60174724237

Received: 11 March 2011 Accepted: 15 December 2011 Published: 21 February 2012

Citation: Mohammed Saghir SA, Al-Hassan FM, Ali Alsalahi OS, Abdul-Alaziz Alhariry AE, Baqir HS. Frequencies of HBV, HCV, HIV, and Syphilis Markers Among Blood Donors: A Hospital-Based Study in Hodeidah, Yemen. Trop J Pharm Res 2012; 11(1):132-136 doi: 10.4314/tjpr.v11i1.17

© 2012 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: This study aimed to determine the frequency rates of human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis among blood donors.

Methods: Physically fit persons aged 18 – 48 years who came for blood donation at the blood bank unit of the military hospital in Hodeidah, Yemen (MHH) from November 2008 to October 2010 were screened using standard diagnostic (SD) reagents. Based on the results, donors with clinical anemia and with history of jaundice were excluded.

Results: A total of 1,483 male donors (96 % semi-voluntary and 4 % replacement donors) with a mean age of 24.3 years were enrolled in this study. The frequencies of HBV, HCV, HIV and syphilis in the samples were 2.35, 0.79, 0.14, and 0.34 %, respectively. Compared with the first year, the decrease in HBV and HCV positive cases and the increase in HIV and syphilis positive cases in the second year were not statistically significant (p = 0.91, p = 0.74, p = 0.72, and p = 0.92, respectively).

Conclusion: While the frequency rate of transfusion-transmitted infections (TTIs) is low, it remains a major problem in blood transfusion. Proper protocol should be applied in selecting and screening donors to safeguard the health of people receiving blood transfusions.

Keywords: Transfusion-transmitted infections, Blood donors, Human immunodeficiency virus, Hepatitis B, Hepatitis C, Syphilis