Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Intermittent Preventive Therapy and Treatment of Malaria during Pregnancy: A Study of Knowledge among Pregnant Women in Rufiji District, Southern Tanzania

Ritah Mutagonda¹, Appolinary AR Kamuhabwa¹ , Siriel Massawe², Rose Mpembeni³

¹Unit of Pharmacology and Therapeutics, School of Pharmacy; ²Department of Obstetrics and Gynaecology, School of Medicine; ³Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

For correspondence:- Appolinary Kamuhabwa Email: akamuhabwa@muhas.ac.tz Tel:+255757576985

Received: 22 February 2012 Accepted: 18 August 2012 Published: 18 October 2012

Citation: Mutagonda R, Kamuhabwa AA, Massawe S, Mpembeni R. Intermittent Preventive Therapy and Treatment of Malaria during Pregnancy: A Study of Knowledge among Pregnant Women in Rufiji District, Southern Tanzania. Trop J Pharm Res 2012; 11(5):835-845 doi: 10.4314/tjpr.v11i5.18

© 2012 The authors.
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Abstract

Purpose: To assess the knowledge and awareness of pregnant women regarding the use of sulfadoxine-pyrimethamine (SP) for intermittent preventive therapy (IPT) and artemether-lumefantrine (ALu) for treatment of malaria during pregnancy.

Methods: The study was conducted in Rufiji district, southern Tanzania from March 2011 to September 2011. Four hundred and seventy (470) pregnant women in their second and third trimesters were interviewed when attending antenatal clinics at the selected hospitals, health centers and dispensaries. Focus group discussions (FGDs) were also conducted with 46 pregnant women at the health facilities in the district.

Results: More than half (54.3 %) of pregnant women did not know if SP it was used for IPT. Most women (76.6 %) did not know the use of SP for IPT in relationship with gestation age. Overall, the results show that most women had very low knowledge about the use of SP for IPT. Forty three (9.1 %) pregnant women reported to have had malaria during their current pregnancies. The antimalarials reported to be used by pregnant women were quinine 18(42.9 %), SP (23.8 %), ALu (21.4%) and sulphamethoxyprazine-pyrimethamine (2.4%). Irrespective of the gestation age of pregnancy, almost all (98.3 %) pregnant women perceived ALu as unsafe drug to be used during pregnancy.

Conclusion: Most pregnant women had minimum knowledge about the use and benefits of SP for IPT and ALu for treatment of malaria during pregnancy. Some erroneous beliefs about the safety of ALu during pregnancy were also identified among pregnant women. For effective implementation of IPT policy and treatment of malaria during pregnancy, pregnant women should be sensitized and educated on the use and benefits of antimalarial drugs.

Keywords: Artemether-lumefantrine, Antenatal clinic, Knowledge, Pregnant women, Sulfadoxine-pyrimethamine