Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

A Review of the Secondary Metabolites and Biological Activities of Tinospora crispa (Menispermaceae)

Yen Chin Koay , Faheem Amir

School of Chemical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia;

For correspondence:- Yen Koay Email: yckoay.86@gmail.com

Received: 28 March 2012 Accepted: 2 June 2013 Published: 23 August 2013

Citation: Koay YC, Amir F. A Review of the Secondary Metabolites and Biological Activities of Tinospora crispa (Menispermaceae). Trop J Pharm Res 2013; 12(4):641-649 doi: 10.4314/tjpr.v12i4.30

© 2013 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Tinospora crispa Beumee, a herbaceous climber, has been widely used in traditional medicine for treating various ailments such as contusion, septicaemia, fever, fracture, scabies and other tropical ulcers. A wide range of secondary metabolites such as alkaloids, diterpenes, flavones, phenolics, and triterpenes have been isolated, some of which have also shown corresponding biological activities. The current review is an update on the reported pharmacological activities and phytochemical constituents of T. crispa.

Keywords: Antioxidant, Alkaloid, Diterpene, Flavone, Triterpene