Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Hypertension Management and Factors Associated with Blood Pressure Control in Jordanian Patients Attending Cardiology Clinic

Nailya R Bulatova , Al-Motassem Yousef, Salah Dein AbuRuz, Rana Abu Farha

Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, The University of Jordan, Amman, Jordan;

For correspondence:- Nailya Bulatova Email: nyounes@ju.edu.jo Tel:+96265355000

Received: 5 October 2012 Accepted: 12 July 2013 Published: 18 October 2013

Citation: Bulatova NR, Yousef A, AbuRuz SD, Farha RA. Hypertension Management and Factors Associated with Blood Pressure Control in Jordanian Patients Attending Cardiology Clinic. Trop J Pharm Res 2013; 12(5):827-833 doi: 10.4314/tjpr.v12i5.25

© 2013 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To assess modifiable clusters of cardiovascular risk factors and patterns of antihypertensive drugs use as well as identify clinical characteristics associated with blood pressure control in Jordanians.

Methods: A cross-sectional observational study was conducted in cardiology outpatient clinics at two hospitals in Amman, Jordan. Outcomes studied were prevalence of cardiovascular risk factors, patterns of antihypertensive medication use, rate of blood pressure control and factors associated with such control.

Results: The number of concomitant medical conditions was high: diabetes mellitus (51 %), dyslipidemia (82 %), coronary artery disease (71 %), history of acute coronary syndrome (37 %) or coronary revascularization (64 %). Hypertension was controlled in 44 % of patients. Average number of antihypertensive medications was 2.38 ± 1.21. The most commonly prescribed monotherapy medications were beta-blockers (48 %), followed by angiotensin-converting enzyme inhibitors (ACEIs) with 28 % and angiotensin II receptor blockers (ARBs) with 23 %. Among all patients, beta-blockers (67 %) were also the most prescribed, followed by ACEIs (47 %) and ARBs (41%). Multivariate logistic regression analysis revealed inverse association between BP control and the presence of diabetes mellitus.

Conclusion: There is inadequate cardiovascular risk assessment and control of blood pressure in hypertensive patients in Jordan. Several practical measures need to be taken urgently to mitigate these deficiencies.

Keywords: Hypertension management, Blood pressure control, Cardiology clinic, Cardiovascular risk factors, Antihypertensive medications