Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Antioxidant, antimicrobial and antiproliferative activities of peel and pulp extracts of red and white varieties of Ipomoea batatas (L) Lam

Shakeela Naz¹, Syed Ali Raza Naqvi¹ , Zulfiqar Ali Khan¹, Asim Mansha¹, Matloob Ahmad¹, Ameer Fawad Zahoor¹, Zaib Hussain²

¹Department of Chemistry, Government College University, Fiasalabad-38040; ²Institute of Chemistry, University of the Punjab, Lahore-54000, Pakistan.

For correspondence:- Syed Raza Naqvi Email: draliraza@gcuf.edu.pk

Accepted: 10 August 2017 Published: 30 September 2017

Citation: Naz S, Raza Naqvi SA, Khan ZA, Mansha A, Ahmad M, Zahoor AF, et al. Antioxidant, antimicrobial and antiproliferative activities of peel and pulp extracts of red and white varieties of Ipomoea batatas (L) Lam. Trop J Pharm Res 2017; 16(9):2221-2229 doi: 10.4314/tjpr.v16i9.25

© 2017 The authors.
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Abstract

Purpose: To investigate the antioxidant, antibacterial and anticancer potentials of methanol and ethanol extracts of the peel and pulp of red and white species of Ipomoea batatas (L.) fruit.

Methods: Total phenolic contents and flavonoids were determined using chemical assays. Antioxidant studies were carried out using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay, inhibition of linoleic acid peroxidation assay and reducing power assay. Antibacterial and antiproliferative activities of extracts were determined using disc diffusion and MDBK cancer cell line inhibition methods, respectively.

Results: The extract of peels of red specie (PERS) showed total phenolic contents (TPC) 8.9 mg gallic acid equivalent (GAE)/g dry extract and flavonoids 6.5 mg catechin equivalent (CE)/g dry extract. The extract of PERS also showed promising DPPH free radical scavenging activity, inhibition of linoleic acid peroxidation and reducing power activity. However, mild antibacterial and anti-proliferative activities were noted except that the extract showed significant inhibition of Bacillus subtilis growth.

Conclusion: The results indicate that the peel and the pulp of red sweet potato (SP) specie are rich in antioxidants and can potentually be processed as antioxidant food supplements.

Keywords: Ipomoea batatas (L.) Lam, Sweet potato, Phenolic content, Antioxidants, Antibacterial activity, Antiproliferative activity