Belgin Erdem1,
Eyup Bagci2,
Gulden Dogan2 
,
Ekrem Aktoklu1,
Alpaslan Dayangac1
For correspondence:- Gulden Dogan Email: gdogan@firat.edu.tr
Accepted: 20 July 2018 Published: 31 August 2018
Citation: Erdem B, Bagci E, Dogan G, Aktoklu E, Dayangac A. Chemical composition and antimicrobial activities of essential oil and ethanol extract of Cyperus fuscus L burs from Turkey. Trop J Pharm Res 2018; 17(8):1637-1643 doi: 10.4314/tjpr.v17i8.24
© 2018 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
Purpose: To investigate the chemical composition of the essential oil of Cyperus fuscus burs as well as the antimicrobial activities of the ethanol extracts and essential oil.
Methods: Fresh burs roots of C. fuscus were collected at the flowering stage in an open area in Güdül (Ankara, Turkey). Preparation of the ethanol extract, hydrodistillation of the essential oil, GC-FID-MS analysis, and agar diffusion and MIC agar dilution assays were performed to determine various parameters for the oil and extracts.
Results: The major compounds of the essential oil were dehydroaromadendrene (10.7 %), azulenone (8.5 %), α-selinene (7.5 %), α-ylangene (6.0 %) and β-caryophyllene (5.6 %). The essential oil of Cyperus fuscus exhibited activity against Gram-negative bacteria with minimum ınhibitory concentration (MIC) values ranging from 1000 to 31.25 μl/mL. Similarly, the ethanol extract of the burs showed good antimicrobial activity with the MIC of the ethanol extracts on ranging from 1000 μg/mL (Escherichia coli) to 250 µg/mL (Pseudomonas. Aeruginosa, p < 0.05). However, the ethanol extract was inactive against yeast strains.
Conclusion: Thus, the essential oil and ethanol extract of the studied plant can potentially be used as antimicrobial agent.
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