Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Effect of Qianliexin capsule on quality of life, NIH-CPSI score and IIEF-5 score in patients with prostatitis complicated with erectile dysfunction

Chen Xiaosong¹ , Wang Ping²

¹Urinary Department of Xuanwu Hospital, Capital Medical University; ²General Practice in Health Service Center, Baizhifang Community of Xicheng District, Beijing City 100054, China.

For correspondence:- Chen Xiaosong Email: zv1169@163.com

Accepted: 27 November 2018 Published: 27 December 2018

Citation: Xiaosong C, Ping W. Effect of Qianliexin capsule on quality of life, NIH-CPSI score and IIEF-5 score in patients with prostatitis complicated with erectile dysfunction. Trop J Pharm Res 2018; 17(12):2489-2495 doi: 10.4314/tjpr.v17i12.27

© 2018 The authors.
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Abstract

Purpose: To study the influence of Qianliexin capsule on quality of life, NIH-CPS Index, and 5-item version of the 15-item International Index of Erectile Function (IIEF-5) scores in patients with prostatitis complicated with erectile dysfunction (ED).

Methods: Patients with prostatitis complicated with ED (128) who were treated from November 2015 to December 2017 participated in this study. The patients were assigned to two groups (64 per group) according to the treatment given: study group which was given routine treatment plus Qianliexin capsule, and control group which received routine treatment only. Clinical effectiveness, adverse reactions, Quality of Life-Bref (QOL-BREF) scores, etc, of the two groups were determined.

Results: The QOL-BREF score of the study group was significantly higher than that of the control group (p < 0.05). While NIH-CPSI scores were significantly decreased in both groups, the decrease in the study group was lower (p < 0.05). In contrast, IIEF-5 score significantly increased in both groups, but the increase in the study group was higher than in control (p < 0.05).

Conclusion: Qianliexin capsule is an effective and reasonably safely drug for enhancing the quality of life, NIH-CPSI and IIEF-5 scores, as well as the lecithin bodies in prostatitis patients with ED.

Keywords: Qianliexin capsule, Prostatitis, Erectile dysfunctionÂ NIH-CPSI score, IIEF-5 score