Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Efficacy of calcium sodium phosphosilicate containing dentifrice in reducing dentin hypersensitivity compared to other dentifrices with dentin tubule occluding molecules: A systematic review

Sunil Kumar Vaddamanu¹, Saad Muhammad AlQahtani², Ravi Kadur Sundarraj³ , Raghavendra Reddy Nagate⁴, Vijay Apparaju⁵

¹Department of Dental Technology; ²Department of Periodontics and Community Dental Sciences, College of Dentistry; ³Department of Pediatric Dentistry and Orthodontic Sciences, College of Dentistry; ⁴Department of Periodontics and Community Dental Sciences, College of Dentistry, King Khalid University, Abha, Kingdom of Saudi Arabia; ⁵Department of Periodontics, Dr Vijay's Multispeciality Dental Care, Bangalore, India.

For correspondence:- Ravi Sundarraj Email: sundarraj@kku.edu.sa

Accepted: 15 March 2019 Published: 30 April 2019

Citation: Vaddamanu SK, AlQahtani SM, Sundarraj RK, Nagate RR, Apparaju V. Efficacy of calcium sodium phosphosilicate containing dentifrice in reducing dentin hypersensitivity compared to other dentifrices with dentin tubule occluding molecules: A systematic review. Trop J Pharm Res 2019; 18(4):877-888 doi: 10.4314/tjpr.v18i4.28

© 2019 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To assess the effectiveness of calcium sodium phosphosilicate in reducing dentin hypersensitivity compared to other dentin tubule occluding molecules.

Methods: A structured research question was formulated, and an electronic search of available literature was carried out via PubMed, Google Scholar, and Scopus. A hand search as well as a gray literature search were also carried out. The search produced a total of 67 articles. Of these, only eight articles were eligible to be included in our review. Risk of bias and study quality were checked using Cochrane tool. The review was registered in The International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD42018096200.

Results: The results show a reduction in dentin hypersensitivity with calcium sodium phosphosilicate compared to many other molecules. However, nanohydroxyapatite showed a better desensitizing effect compared to Novamin.

Conclusion: According to the available evidence, 5 % calcium sodium phosphosilicate containing toothpaste is more effective reducing dentin hypersensitivity compared to many other dentinal tubule occluding molecules.

Keywords: Dentin hypersensitivity, novamin, calcium sodium phosphosilicate, potassium nitrate