Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Hypertension-related knowledge, medication adherence and health-related quality of life (HRQoL) among hypertensive patients in Islamabad, Pakistan

Muhammad Amer¹, Nisar-Ur-Rahman ¹, Saeed-Ur-Rashid Nazir² , Atif Raza³, Humayun Riaz⁴, Saleha Sadeeqa⁵, Misbah Sultana³

¹Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus; ²Faculty of Pharmacy, University of Sargodha, Sargodha; ³University College of Pharmacy, University of Punjab; ⁴Rashid Latif College of Pharmacy; ⁵Institute of Pharmacy, Lahore College for Women University, Lahore, Pakistan.

For correspondence:-

Accepted: 17 April 2019 Published: 31 May 2019

Citation: Amer M, N, Nazir S, Raza A, Riaz H, Sadeeqa S, et al. Hypertension-related knowledge, medication adherence and health-related quality of life (HRQoL) among hypertensive patients in Islamabad, Pakistan. Trop J Pharm Res 2019; 18(5):1123-1132 doi: 10.4314/tjpr.v18i5.30

© 2019 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To determine knowledge regarding hypertension, adherence to medication and Health-Related Quality of Life (HRQoL), and their associations in hypertensive patients in Pakistan.

Methods: A cross-sectional study was conducted among 384 hypertensive patients attending a tertiary health care public sector hospital in Islamabad, Pakistan. Data were collected using knowledge questionnaire regarding hypertension, Morisky Medication Adherence Scale, and EuroQol (EQ-5D) scale.

Results: The mean systolic and diastolic blood pressures of the 384 patients were 140.39 ± 15.485 and 88.74 ± 10.683 mmHg, respectively. The coefficient of correlation between knowledge regarding hypertension and adherence was 0.638 (p < 0.001), showing a positive association. The correlation coefficient between knowledge and HRQoL was 0.709 (p < 0.001), suggesting a good association. The correlation coefficient between adherence to medication and HRQoL was 0.545 (p < 0.001), which indicated a positive correlation.

Conclusion: These results indicate that there are statistically significant associations between hypertension knowledge and HRQoL, hypertension knowledge and medication adherence, and between adherence and HRQoL in the hypertensive patients studied.

Keywords: Hypertension, Knowledge, Medication adherence, Blood pressure