Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Traditional uses, chemical constituents and pharmacological effects of Boschniakia rossica: A systematic review

Liying Fang¹ , Jun Ren²

¹Department of Bioengineering, School of Life Science and Technology, Changchun University of Science and Technology, Changchun 130022; ²Research Institute of Forest, Jilin Provincial Academy of Forest Science, Changchun 130033, China.

For correspondence:- Liying Fang Email: liyingfan5@126.com Tel:+8643185583892

Accepted: 17 November 2019 Published: 31 December 2019

Citation: Fang L, Ren J. Traditional uses, chemical constituents and pharmacological effects of Boschniakia rossica: A systematic review. Trop J Pharm Res 2019; 18(12):2643-2651 doi: 10.4314/tjpr.v18i12.25

© 2019 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To undertake a review on the morphology, traditional uses, phytochemistry and pharmacology of Boschniakia rossica, a plant with a long history of usage in Chinese traditional medicine.

Methods: Available literature on the ethnopharmacological uses of B. rossica from 1967 to 2018 were selected via various databases, such as ScienceDirect, NCBI, Springerlink, Taylor & Francis and CNKI.

Results: A variety of phytochemical studies demonstrated that B. rossica contains more than 100 chemical constituents, among which boschnaside, boschniakine, 7-deoxy 8-epiloganic acid, (4R)-4-hydroxymethyl-boschnialactone are predominant. Studies showed that isolates and crude extracts of B. rossica exhibit a wide spectrum of in vitro and in vivo pharmacological effects such as anti-aging, anti-tumor, anti-oxidant, anti-inflammatory and immune enhancement. It was revealed that iridoids, carbohydrates and glycosides are perhaps responsible for most of the biological activities shown by this plant. However, the bio-active compounds and their underlying mechanisms of action have not yet been investigated in detail.

Conclusion: B. rossia has received tremendous research attention. Phytochemical and pharmacological studies have provided scientific bases for validation of the traditional uses of the plant.

Keywords: Boschniakia rossica, Traditional herb, Pharmacology, Chemical components, Boschnaside