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Original Research Article | OPEN ACCESS

Relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three selected Chinese hospitals

Haidong Luo1, Yin Lin1, Jia Li2, Weiguo Xu3

1Psychological Counseling and Treatment Center, Hainan Province Anning Hospital, Haikou, Hainan 570200; 2Department of Psychology, Hainan People's Hospital, Haikou, Hainan 570311; 3Department of Psychiatry, Ningxia Hui Autonomous Region ning' an Hospital (Ningxia Mental Health Center), Yinchuan, Ningxia 750021, China.

For correspondence:-  Weiguo Xu   Email: 21sureger@163.com   Tel:+869512160749

Accepted: 21 December 2020        Published: 31 January 2021

Citation: Luo H, Lin Y, Li J, Xu W. Relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three selected Chinese hospitals. Trop J Pharm Res 2021; 20(1):183-190 doi: 10.4314/tjpr.v20i1.26

© 2021 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To determine the relationship between adherence to anti-diabetic medication and depression among patients with diabetes mellitus in three hospitals in Chinese.
Methods: This research utilized a quantitative and descriptive design, and included 200 diabetic patients who fulfilled the inclusion criteria for recruitment through a convenient sampling technique. The study applied Beck’s depression inventory II scale for assessment of depression, and a questionnaire for adherence to anti-diabetic medication.
Results: A total of 64 (32 %) participants had diabetes for 6 to 10 years. There was a high level of adherence to anti-diabetic medication in 96 patients (48 %); 74 participants (37 %) had moderate adherence to anti-diabetic medication, while 30 patients (15 %) had low adherence. A majority of the patients (181, 90.5 %) had no depression. Six (6) patients (3 %) had mild mood disturbance, 2 patients (1 %) had borderline clinical depression, while 11patients (5.5 %) experienced moderate depression. Adherence to anti-diabetic medication was not associated with depression (p = 0.068). However, depression was associated with age ? 50 years (p = 0.041), female sex (p = 0.043), long duration of illness (> 5-years) (p = 0.048), and presence of one or more comorbidities (p = 0.049). 
Conclusion: There was no association between adherence to anti-diabetic medication and depression among diabetic patients.

Keywords: Adherence to anti-diabetic medication, Beck’s depression inventory II, Depression, Diabetes mellitus

Impact Factor
Thompson Reuters (ISI): 0.6 (2023)
H-5 index (Google Scholar): 49 (2023)

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