Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Short-term and long-term outcomes of zirconium dioxide-based dental restorations, and it effects on masticatory function

Guodong Peng¹, Hui Yan²

¹Department of Stomatology, Jingzhou No. 1 People's Hospital and First Affiliated Hospital of Yangtze University, Jingzhou, China; ²The First People's Hospital of Yichang, The People's Hospital of China Three Gorges University, Yichang 443000, China.

For correspondence:- Hui Yan Email: yanhui_20161103@163.com Tel:+8613545857736

Accepted: 26 May 2022 Published: 30 June 2022

Citation: Peng G, Yan H. Short-term and long-term outcomes of zirconium dioxide-based dental restorations, and it effects on masticatory function. Trop J Pharm Res 2022; 21(6):1301-1307 doi: 10.4314/tjpr.v21i6.24

© 2022 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To investigate the short- and long-term outcomes of zirconium dioxide-based restorations (ZDBR), and changes in masticatory function (MF).

Methods: One hundred and two (102) patients who received restorative dentistry procedures were divided into two groups using random number method: control group (CG, n = 52, alloy-based restorations) and study group (SG, n = 50, zirconium dioxide restorations). Treatment efficacy, quality, levels of IL-8 and IL-6 in gingival sulcus fluid, and satisfaction scores were compared.

Results: The SG showed better outcomes and restoration quality than CG. After restoration, SG showed greater decrease in IL-8 and IL-6 levels than CG (p < 0.05), while IL-8 and IL-6 levels were higher in SG and CG than those before restoration (p < 0.05). After 1 and 6 months of restoration, SG showed increased dental appearance satisfaction and a higher success rate than CG (p < 0.05). Occlusal force and MF were significantly improved in both groups (p < 0.05). Gingival index, bleeding index, plaque index, and tooth looseness after restoration significantly improved in both groups, but were lower in SG than in CG (p < 0.05).

Conclusion: In oral restorations, ZDBR is more effective in terms of short-term and long-term outcomes. Patients' occlusal force and MF are better restored, and patients' quality of life is also significantly improved. Therefore, ZDBR in oral restorations is feasible but further clinical trials are required.

Keywords: Restorative dentistry, Zirconia restorations, Short- and long-term, Masticatory function, Occlusal force