Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Effect of combined use of home blood pressure monitoring and nifedipine on blood pressure compliance and quality of life of patients with essential hypertension

Yingchao Wang , Yunru Wang, Hua Du

Cardiovascular Medicine II, Jiaozuo Coal Industry (Group) Co. Ltd, Central Hospital, No. 1 Jiankang Street Jiefang District, Jiaozuo City, Henan Province, China;

For correspondence:- Yingchao Wang Email: w289232231@163.com

Accepted: 31 August 2022 Published: 30 September 2022

Citation: Wang Y, Wang Y, Du H. Effect of combined use of home blood pressure monitoring and nifedipine on blood pressure compliance and quality of life of patients with essential hypertension. Trop J Pharm Res 2022; 21(9):2009-2016 doi: 10.4314/tjpr.v21i9.27

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Abstract

Purpose: To investigate the effect of combination of home blood pressure monitoring (HBPM) and nifedipine on blood pressure compliance and quality of life in patients with essential hypertension.

Methods: One hundred and twenty essential hypertension patients admitted to Jiaozuo Coal Industry (Group) Co. Ltd Central Hospital from February 2020 to February 2021 were retrospectively studied. They were equally divided into study group (SG) and control group (COG) according to the order of admission. All patients were treated with nifedipine. Blood pressure was regularly measured in COG patients in the consulting room, while for SG patients, blood pressure was measured at home. Treatment compliance, blood pressure-related indices and quality of life of the two groups were determined.

Results: Treatment compliance values of patients in SG at 6 weeks (T2) and 12 weeks (T3) were significantly better than the corresponding values for patients in COG (p < 0.05). The related indices of blood pressure at T2 and T3 were significantly better in SG than in COG (p < 0.05), with higher blood pressure compliance at T2 and T3 in SG (60 and 70 %, respectively) than in COG (p < 0.05). The quality-of-life scores at T3 in SG were significantly higher than those in COG (p < 0.05).

Conclusion: The combined use of HBPM and nifedipine improves treatment compliance, enhances the levels of related indices of blood pressure, increases blood pressure compliance, and quality of life of patients with essential hypertension. Therefore, the combined therapy merits further investigation on a larger scale.

Keywords: Home blood pressure monitoring, Nifedipine, Essential hypertension, Quality of life