Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Application of two-dimensional speckle tracking imaging in the follow-up of patients with coronary heart disease treated with metalol

Mengyuan Li¹ , Chunwang Zhou², Li Li¹, Yi Ma¹, Biqiong Zhao¹

¹Tangshan Worksâ€™ Hospital, North China University of Science and Technology Affiliated Hospital, Tangshan, China; ²Department of Anesthesiology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.

For correspondence:- Mengyuan Li Email: hxz20130831@163.com Tel:+8615833153013

Accepted: 25 February 2023 Published: 31 March 2023

Citation: Li M, Zhou C, Li L, Ma Y, Zhao B. Application of two-dimensional speckle tracking imaging in the follow-up of patients with coronary heart disease treated with metalol. Trop J Pharm Res 2023; 22(3):619-624 doi: 10.4314/tjpr.v22i3.20

© 2023 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: To investigate the application of two-dimensional speckle tracking imaging (2D-STI) in the follow-up of patients with coronary heart disease (CHD) who were treated with metalol.

Methods: A total of 100 patients with CHD (CHD group) who were treated with metalol and had undergone percutaneous coronary intervention (PCI) at Tangshan Works’ Hospital, Tangshan, China, and another 100 healthy people (control group) were enrolled in this study. Prior to and after 6 months of treatment, echocardiography was performed on patients in control and CHD groups, respectively, and the wall motion score was calculated. The 2D-STI was used to obtain systolic peak longitudinal strain value (SLs), global peak longitudinal strain (GSL) and early diastolic peak longitudinal strain rate (SrLe) in the early diastolic period of 6 wall basal segments, middle segments, and apical segments of the left ventricle.

Results: The wall motion score index (WMSI) of CHD group was higher than that of the control group, while the WMSI of CHD group after treatment was significantly lower than the value before treatment, (p < 0.05). In 2D-STI, the SLs, SrLe and GLS of patients after 6 months of treatment were significantly higher than those before treatment (p < 0.05).

Conclusion: Thus, 2D-STI can be used to quantify the motion of the chamber wall and the effect of PCI surgery, and it also provides a stable new index and technique for evaluating the effects of treatment of CHD.

Keywords: Coronary heart disease, Metalol, Percutaneous coronary intervention (PCI) two-dimensional speckle tracking imaging (2D-STI), Speckle tracking imaging