Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Comparison of nerve block anesthesia and local infiltration anesthesia with lidocaine hydrochloride in primary root canal treatment of mandibular molars

Shuangshuang Geng¹, Jian Wang², Xiaobei Bai¹, Yan Hou³, Junke Li¹, Jiandong Ban¹

¹Department of Oral Medicine, Hebei Eye Hospital, Xingtai 054000, China; ²Department of Oral and Maxillofacial Surgery, Hebei Eye Hospital, Xingtai 054000, China; ³Ophthalmology Clinic, Hebei Eye Hospital, Xingtai 054000, China.

For correspondence:- Jiandong Ban Email: 2020020568@stu.cdut.edu.cn Tel:+8615631901359

Accepted: 30 March 2023 Published: 29 April 2023

Citation: Geng S, Wang J, Bai X, Hou Y, Li J, Ban J. Comparison of nerve block anesthesia and local infiltration anesthesia with lidocaine hydrochloride in primary root canal treatment of mandibular molars. Trop J Pharm Res 2023; 22(4):873-878 doi: 10.4314/tjpr.v22i4.21

© 2023 The authors.
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Abstract

Purpose: To investigate and compare the analgesic effects of nerve block anesthesia and local infiltration anesthesia in one-visit root canal therapy of mandibular molars.

Methods: A total of 120 patients who underwent one-visit root canal therapy for mandibular molars were divided into nerve block group (n = 76) and local infiltration group (n = 44). Lidocaine was used to anesthetize the two groups. Perioperative heart rate (HR), diastolic blood pressure (DBP) and systolic blood pressure (SBP) were determined in the two groups. Visual analogue scale (VAS) and Ramsay sedation scale were used to assess postoperative pain and sedation in the two groups. The occurrence of adverse reactions was also compared.

Results: The success rate of the anesthesia in the nerve block group was significantly higher than that in local infiltration group (9 7.37 vs 88.64 %; p < 0.05). There were no significant differences in HR, DBP and SBP levels between the two groups. Over time, VAS and Ramsay scores decreased in both groups, while the VAS and Ramsay scores in the nerve block group were significantly lower than those in the local infiltration group (p < 0.05). The incidence of adverse reactions in the nerve block group was 5.26 %, which was not significantly different from 13.64 % incidence rate in local infiltration group (p > 0.05).

Conclusion: Both anesthesia methods have little effect on hemodynamics in patients undergoing one-visit root canal therapy for mandibular molars, but lidocaine nerve block anesthesia is more effective and has stronger analgesic and sedative effects than lidocaine local infiltration anesthesia.

Keywords: Nerve block anesthesia, Local infiltration anesthesia, Mandibular molars, One-visit root canal therapy, Analgesia, Lidocaine