Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Effect of the combination of respiratory care with bronchodilators on pulmonary function, psychological well-being, and health behaviors in COPD patients

Qundan Zhang , Juan Wang, Shuangping Lu

Department of Respiratory Medicine, The First People's Hospital of Fuyang, 429 North Ring Road, Fuchun Street, Fuyang District, Hangzhou 311400, China;

For correspondence:- Qundan Zhang Email: 153775495@qq.com Tel:+8613588802547

Accepted: 31 October 2023 Published: 30 November 2023

Citation: Zhang Q, Wang J, Lu S. Effect of the combination of respiratory care with bronchodilators on pulmonary function, psychological well-being, and health behaviors in COPD patients. Trop J Pharm Res 2023; 22(11):2381-2388 doi: 10.4314/tjpr.v22i11.19

© 2023 The authors.
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Abstract

Purpose: To investigate the effect of combining respiratory care with bronchodilators on pulmonary function, psychological well-being, and health behavior in patients with Chronic Obstructive Pulmonary Disease (COPD).

Method: A retrospective analysis was conducted with 90 COPD patients treated in the First People's Hospital of Fuyang, Hangzhou, China between January 2021 and January 2023. Patients were divided into budegopher group (26 patients), symbicor group (28 patients), and combination group (36 patients treated with budegopher plus respiratory care). Lung function, psychological state (Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS), Health Behavior Scale (HPL), and any observed adverse reactions among these groups were recorded.

Results: Significant differences were observed in lung function such as forced expiratory volume in 1 sec (FEV1) and forced vital capacity (FVC) among the three groups after treatment. Symbicor group showed superior results compared to budegopher group while combination group showed better improvement than budegopher group, and symbicor group (p < 0.001). Pairwise comparisons of psychological state (SAS and SDS) and health behavior (HPL) revealed variations among groups. Lung function parameters (FEV1, FVC) had negative correlations with negative psychological attitudes (SAS, SDS) and moderate positive correlations with health-promoting behaviors (HPL). Negative psychological attitudes (SAS, SDS) were moderately and negatively correlated with health-promoting behaviors (HPL).

Conclusion: Combining respiratory care with bronchodilators demonstrates notable potential to enhance pulmonary function, alleviate negative psychological states, promote healthful behaviors, and expedite the recovery process for COPD patients. However, subtle variations in the therapeutic effects of different drugs may exist, warranting further investigation.

Keywords: Budegopher, Symbicor, Respiratory care, COPD, Negative attitude, Health behavior