Tropical Journal of Pharmaceutical Research

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ISSN: 1596-5996 (print); 1596-9827 (electronic)-

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Research Article

Methanol Extract of Hydroclathrus clathratus Inhibits Production of Nitric Oxide, Prostaglandin E₂ and Tumor Necrosis Factor-α in Lipopolysaccharide-stimulated BV2 Microglial Cells via Inhibition of NF-κB Activity

RGPT Jayasooriya¹, Dong-Oh Moon², Yung Hyun Choi³, Chang-Hoon Yoon⁴, and Gi-Young Kim^1*

¹Laboratory of Immunobiology, Department of Marine Life Sciences, Jeju National University, Jeju 690-756, ² Department of Biology Education, College of Education, Gyeongsan, Gyeongbuk 712-714, ³Department of Biochemistry, College of Oriental Medicine, Dongeui University, Busan 614-054, ⁴Department of Food and Nutrition, College of Natural Science, Jeju National University, 690-756, Republic of Korea.

For correspondence: E-mail: immunkim@jejunu.ac.kr Tel: +82 64 754 3427; Fax: +82 64 756 3493

Received: 4 March 2011 Revised accepted: 16 September, 2011

Tropical Journal of Pharmaceutical Research, December 2011; 10(6): 723-730

http://dx.doi.org/10.4314/tjpr.v10i6.4

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