Research Article
Methanol
Extract of Myelophycus caespitosus Inhibits the
Inflammatory Response in Lipopolysaccharide-stimulated
BV2 Microglial Cells by Downregulating NF-κB via
Inhibition of the Akt Signaling Pathway
Rajapaksha
Gendara Prasad Tharanga
Jayasooriya1, Chang-Hee Kang1,
Yeon-Jeong Jang1,
Sang-Hyuck Kang1, Matharage Gayani Dilshara1,
Yung Hyun Choi2, Dong-Oh Moon3
and Gi-Young Kim1*
1Laboratory of Immunobiology,
Department of Marine Life Sciences, Jeju National
University, Jeju 690-756, 2Department of
Biochemistry, College of Oriental Medicine, Dongeui
University, Busan 614-054, 3Department of
Biology Education, College of Education, Gyeongsan,
Gyeongbuk 712-714, Republic of Korea.
*For correspondence:
Email:
immunkim@jejunu.ac.kr Tel: +82 64 754
3427; Fax: +82 64 756 3493
Received:
26
March 2012 Revised
accepted: 8 October 2012
Tropical
Journal of Pharmaceutical Research, December 2012;
11(6):
917-924
http://dx.doi.org/10.4314/tjpr.v11i6.7