An Efficient, Green
Chemical Synthesis of the Malaria Drug, Piperaquine
Joseph MD Fortunak1*,
Stephen R Byrn2, Brandon Dyson1,
Zita Ekeocha3, Tiffany Ellison1,
Christopher L King1, Amol A Kulkarni4,
Mindy Lee1, Chelsea Conrad1
and Keeshaloy Thompson1
1Department of Chemistry,
Howard University, Washington, DC, 20059, 2Department
of Industrial and Physical Pharmacy, Purdue University,
West Lafayette, IN 47907 USA, 3St Luke
Foundation – Kilimanjaro School of Pharmacy, Industrial
Pharmacy Training Unit, PO Box 481, Moshi, Tanzania,
4Department of Pharmaceutical Sciences,
Howard University, Washington, DC, USA 20059, 5National
Institute for Pharmaceutical Research & Development,
Federal Ministry of Health, P.M.B. 21, Industrial
Layout, Abuja, Nigeria
*For correspondence:
Email:
jfortunak@comcast.net
Received: 6 July
2012
Revised accepted:
11 June 2013
Tropical Journal of
Pharmaceutical Research, October 2013;
12(5):
791-798