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Original Research Article

 		 

Sensitive and Selective Reversed-Phase High Performance Liquid Chromatographic-UV Spectrophotometric Determination of Dextromethorphan and its CYP2D6 Mediated Metabolite, Dextrorphan in Human Urine

                                                                                                                  

Benjamin U Ebeshi1,2*, Obiageri O Obodozie3 and Oluseye O Bolaji2

1Department of Pharmaceutical & Medicinal Chemistry, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, 2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, 3Department of Medicinal Chemistry & Quality Control, National Institute for Pharmaceutical Research & Development, Abuja, Nigeria

 

*For correspondence: Email: ben.beshi@gmail.com; Tel: +234-8059817538

 

Received: 4 December 2012                                                                  Revised accepted: 24 December 2013

 

Tropical Journal of Pharmaceutical Research, January 2014; 13(2): 281-286

http://dx.doi.org/10.4314/tjpr.v13i2.18  

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