Hypertension Management
and Factors Associated with Blood Pressure Control in
Jordanian Patients Attending Cardiology Clinic
Nailya R Bulatova*, Al-Motassem
Yousef, Salah Dein AbuRuz and Rana Abu Farha
Department of
Biopharmaceutics and Clinical Pharmacy, Faculty of
Pharmacy, The University of Jordan, Amman, Jordan
*For correspondence:
Email:
nyounes@ju.edu.jo; Tel: +962 6
5355000, ext 23350 (23355)
Received: 5 October
2012
Revised accepted:
12 July 2013
Tropical Journal of
Pharmaceutical Research, October 2013;
12(5):
827-833
http://dx.doi.org/10.4314/tjpr.v12i5.25
Abstract
Purpose: To assess modifiable
clusters of cardiovascular risk factors and patterns of
antihypertensive drugs use as well as identify clinical
characteristics associated with blood pressure control
in Jordanians.
Methods: A cross-sectional
observational study was conducted in cardiology
outpatient clinics at two hospitals in Amman, Jordan.
Outcomes studied were prevalence of cardiovascular risk
factors, patterns of antihypertensive medication use,
rate of blood pressure control and factors associated
with such control.
Results: The number of concomitant
medical conditions was high: diabetes mellitus (51 %),
dyslipidemia (82 %), coronary artery disease (71 %),
history of acute coronary syndrome (37 %) or coronary
revascularization (64 %). Hypertension was controlled in
44 % of patients. Average number of antihypertensive
medications was 2.38 ± 1.21. The most commonly
prescribed monotherapy medications were beta-blockers
(48 %), followed by angiotensin-converting enzyme
inhibitors (ACEIs) with 28 % and angiotensin II receptor
blockers (ARBs) with 23 %. Among
all patients, beta-blockers (67 %) were also the most
prescribed, followed by ACEIs (47 %) and ARBs (41%).
Multivariate logistic regression analysis revealed
inverse association between BP control and the presence
of diabetes mellitus.
Conclusion: There is inadequate
cardiovascular risk assessment and control of blood
pressure in hypertensive patients in Jordan. Several
practical measures need to be taken urgently to mitigate
these deficiencies.
Keywords:
Hypertension management,
Blood pressure control, Cardiology clinic,
Cardiovascular risk factors, Antihypertensive
medications.