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Original Research Article
Isolation and
Characterization of Batatasin III and
3,4’-Dihydroxy-5-methoxybibenzyl: A Pair of Positional
Isomers from Sunipia scariosa
JZ Yang1, JH
Jiang1, WJ Wang1,2, YM Zhang1,3,
Y Liu1 and YG Chen1*
1Department of Chemistry,
Yunnan Normal University, Kunming 650500, 2Department
of Traditional Medicine, Yunnan University of
Traditional Chinese Medicine, 3Department of
Environmental and Municipal Engineering, Kunming
Metallurgy School, Kunming, China
*For correspondence:
Email:
ygchen48@gmail.com; Tel:
86-871-65941089
Received: 5 May 2013
Revised accepted: 28
February 2014
Tropical
Journal of Pharmaceutical Research, April 2014;
13(4):
533-535
http://dx.doi.org/10.4314/tjpr.v13i4.7
Abstract
Purpose: To isolate and characterize
chemical compounds of biological importance from the
whole plant of Sunipia scariosa.
Methods: The whole plant of Sunipia
scariosa was extracted with methanol (MeOH) and
chromatographed on silica gel and sephadex LH-20 to
afford the pure isolates. High perfomance liquild
chromatography (HPLC) was used for further purification
of the isolated compounds. Characterization of the
isolated compounds was achieved by 1H and 13C nuclear
magnetic resonance spectroscopy (NMR) and mass
spectrometry (MS).
Results: Batatasin III
(3,3’-dihydroxy-5-methoxybibenzyl) and
3,4’-dihydroxy-5-methoxybibenzyl, a pair of positional
isomers, were isolated from the whole plant of Sunipia
scariosa. The yields of the two isomers were 60 and 40
%, respectively, from the mixture of two compounds.
Conclusion: Batatasin III and
3,4’-dihydroxy-5-methoxybibenzyl, a pair of positional
isomers were successfully isolated from the whole plant
of Sunipia scariosa for the first time.
Keywords: Sunipia scariosa, Batatasin
III, 3,4’-Dihydroxy-5-methoxybibenzyl, Isomers |
