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Original Research Article
Association between
Hepatitis B-Related Knowledge and Health-Related Quality
of Life
Noman ul Haq1,2,
Mohamed Azmi Hassali2, Asrul Akmal Shafie2,
Fahad Saleem2, Maryam Farooqui3,
Hisham Aljadhey4, Fiaz Ud Din Ahmad5
and Qaiser Iqbal1
1Department of Pharmacy,
University of Balochistan, Quetta, Pakistan, 2Discipline
of Social and Administrative Pharmacy, School of
Pharmaceutical Sciences, Universiti Sains Malaysia,
Penang, 3Faculty of Pharmacy, Universiti
Technology MARA, Bertam, Penang, Malaysia, 4College
of Pharmacy, King Saud University, Riyadh, Saudi Arabia,
5Department of Physiology, School of
Pharmaceutical Sciences, Universiti Sains Malaysia,
Penang, Malaysia
*For correspondence:
Email:
nomanhaq79@gmail.com; Tel:
+92-333-7830922
Received: 10 June 2013
Revised accepted: 26 April
2014
Tropical
Journal of Pharmaceutical Research, July 2014;
13(7): 1163-1168
http://dx.doi.org/10.4314/tjpr.v13i7.22
Abstract
Purpose: To evaluate the
association between patient’s knowledge of Hepatitis-B
and Health Related Quality of Life (HRQoL).
Methods: A cross sectional,
descriptive study was undertaken with 390 hepatitis-B
patients attending two public hospitals in Quetta City,
Pakistan. Knowledge of hepatitis-B was assessed using a
pre-validated questionnaire. European Quality of Life
scale was used for the assessment of HRQoL. Descriptive
analysis was used to elaborate patients’ demographic
characteristics while inferential statistics were
applied to report the association among study variables.
Spearman’s rho correlation was used to identify the
association between variables.
Results: Out of 390, (230, 59.5 %)
were males and the mean age of the subjects was 36.2 ±
9.2 years. One hundred and three (26 %) had primary
level of education and 109 (27.9 %) were employees in
the private sector. Eighty four (21 %) had a monthly
income of between 10001-15000 Pakistan rupees (1 PKR =
0.0115527 USD) with 272 (69.7 %) respondents resident in
urban areas. Mean HRQoL and Hepatitis-B related
knowledge (HBRK) scores were categorized as poor (0.37±
0.3) and (8.52 ± 2.7) respectively. The correlation
coefficient between HRQoL and HBRK was -0.102 (p <
0.001), indicating a week negative association between
the study variables.
Conclusion: The findings indicate a
negative association between Hepatitis-B related
knowledge and HRQoL. Therefore, providing
disease-related knowledge to patients does not
necessarily improve HRQoL. More attention should be
given to identify individual factors that affect HRQoL
among patients with Hepatitis-B.
Keywords: Health
related quality of life, HRQoL, Hepatitis-B,
Disease-related knowledge, Association |