Indexed by Science Citation Index (SciSearch), International Pharmaceutical Abstract, Chemical Abstracts, Embase, Index Copernicus, EBSCO, African Index Medicus, JournalSeek, Journal Citation Reports/Science Edition, Directory of Open Access Journals (DOAJ), African Journal Online, Bioline International, Open-J-Gate

ISSN: 1596-5996 (print); 1596-9827 (electronic)-

Home | Back Issues | Current Issue | Review manuscript | Submit manuscript


	This Article
	Abstract
	Full-text
	Table of contents
	Comments
	Letters
	Comments to Editor

	e-mail Alert
	Sign Up

Review Article

Multiparticulate Drug Delivery Systems for Controlled Release

NS Dey*, S Majumdar and MEB Rao

Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Khodasinghi, Berhampur, Orissa760010, India

*Corresponding author: E-mail: niladrisekhar111@gmail.com Tel: +91-09861352986

Tropical Journal of Pharmaceutical Research, September 2008; 7(3): 1067-1075

Abstract

Pharmaceutical invention and research are increasingly focusing on delivery systems which enhance desirable therapeutic objectives while minimising side effects. Recent trends indicate that multiparticulate drug delivery systems are especially suitable for achieving controlled or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. The release of drug from microparticles depends on a variety of factors including the carrier used to form the multiparticles and the amount of drug contained in them. Consequently, multiparticulate drug delivery systems provide tremendous opportunities for designing new controlled and delayed release oral formulations, thus extending the frontier of future pharmaceutical development.

Keywords: Dose dumping, Microparticles, Multiparticulate delivery system, Delayed release