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Original
Research Article
GC-MS Analysis of
Insecticidal Leaf Essential Oil of Pyrenacantha
Staudtii Hutch and Dalz (Icacinaceae)
Abiodun Falodun1, R Siraj2,
Muhammad Iqbal Choudhary 2
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University
of Benin, Benin City 300001, Nigeria, 2H.E.J.
Research Institute of Chemistry, International Center
for Chemical Sciences, University of Karachi, Karachi
75270, Pakistan
Received:
20
September 2008
Revised accepted:
28
December 2008
Tropical
Journal of Pharmaceutical Research, April
2009; 8(2):
139-143
Abstract
Purpose:
Insecticides have been known to cause serious toxicological and
environmental problems. Hence, the insecticidal activity
and chemical composition of a local medicinal plant was
investigated.
Methods:
Steam distillation of P.staudtii leaves was carried out using a
Clavenger apparatus in order to obtain the volatile
oils. Gas chromatography/mass spectrometric (GC/MS)
analyses (DB-5 Optima-5
column) of the essential oil were performed and
its insecticidal activity determined.
Results:
GC-MS spectrometry showed that the major chemical components of the oil
were tetradecanoic acid (22 %), hexanoic acid, α-phellandrene
(13 %), and citronellol sp. (7 %). The work also
revealed significant insecticidal activity of 80 % and
60 % against Rhyzopertha dominica and
Tribolium castaneum, respectively.
Conclusion:
The study established the chemical composition and
insecticidal activity of the essential oil of the plant
leaf. Future formulation studies, toxicity profile and
possible mechanism of action may lead to the development
of a potential insecticidal product.
Keywords:
Pyrenacantha stautii leaf, GC-MS, Leaf
essential oils, Insecticidal. |
