Indexed by Science Citation Index (SciSearch), International Pharmaceutical Abstract, Chemical Abstracts, Embase, Index Copernicus, EBSCO, African Index Medicus, JournalSeek, Journal Citation Reports/Science Edition, Directory of Open Access Journals (DOAJ), African Journal Online, Bioline International, Open-J-Gate

ISSN: 1596-5996 (print); 1596-9827 (electronic)-

Home | Back Issues | Current Issue | Review manuscript | Submit manuscript


	This Article
	Abstract
	Full-text
	Table of contents
	Comments
	Letters
	Comments to Editor

	e-mail Alert
	Sign Up

Research Article

Antimicrobial Resistance of Urinary Escherichia coli Isolates

Müjde Eryılmaz^1*, Merve Eylül Bozkurt¹, Muharrem Murat Yildiz² and Ahmet Akin¹

¹Department of Pharmaceutical Microbiology, Faculty of Pharmacy, University of Ankara,

²Health Ministry, Etlik Lokman Hekim Hospital, Etlik, Ankara, Turkey

*Corresponding author: E-mail: mujdeyuce@yahoo.com Tel: +90 312 203 31 85

Received: 11 September 2009 Revised accepted: 19 February 2010

Tropical Journal of Pharmaceutical Research, April 2010; 9(2): 205-209

Abstract

Purpose: To investigate the antimicrobial resistance rate of 110 E. coli strains, isolated from UTIs in Etlik Lokman Hekim Hospital, Etlik, Ankara, Turkey.

Methods: API-20E System (bioMerieux, France) was used to identify E. coli isolates. Antimicrobial susceptibility testing was conducted on Mueller-Hinton Agar plates (Merck, Germany) using agar disc diffusion method and the results were expressed as susceptible or resistant according to the criteria recommended by the Clinical and Laboratory Standarts Institute (CLSI).

Results: The resistance rates detected were 56 % to ampicillin, 24 % to ampicillin sulbactam, 9 % to gentamicin, 15 % to ciprofloxacin, 36 % to trimethoprim sulfamethoxazole, 12 % to cefazolin, and 7 % to cefuroxime. All isolates tested were susceptible to fosfomycin and nitrofurantoin.

Conclusion: When the high resistance rates in Turkey are taken into consideration, antimicrobial agent usage policies and empirical therapies should be based on antimicrobial resistance surveillance studies.

Keywords: Urinary tract infections, Escherichia coli, Antimicrobial resistance.